DETAILS, FICTION AND LDN-27219 PHARMACOLOGICAL PROPERTIES

A single significantly attention-grabbing compound is LDN-27219. When most tTG inhibitors are intended to bind for the protein crosslinking Lively web-site, LDN-27219 as an alternative binds into the nucleotide binding pocket on the enzyme although it is in its closed-point out conformation, and stabilizes that conformation to stop crosslinking act